The CCCB was founded by John Quackenbush and Mick Correll in 2009, and is one of many multidisciplinary research centers that have been established under the Institute's new Strategic Plan.
Genomic-enabled technologies such as DNA microarrays, SNP arrays, proteomics, metabolomics, and Next-Generation DNA sequencing have drastically changed the way in which we approach research questions in basic, clinical, and translational research. The result is that the biological sciences are increasingly evolving into information sciences in which managing and analyzing large and increasingly complex datasets are essential elements for research success. As a result, computation is evolving to take a place alongside theory and experiment as one of three pillars necessary to support scientific inquiry in modern research enterprises. As technologies have matured and our ability to generate data has improved, the question has increasingly become how to turn data into knowledge and knowledge into understanding.
Our goal in establishing a Center for Cancer Computational Biology (CCCB) is to begin to build the infrastructure necessary to address these needs and to establish the research capacity to address the next generation of questions arising from the application of new technologies across the research enterprise in order to keep Dana-Farber at the leading edge of cancer research.